The basic research within the Sealy Center for Structural Biology & Molecular Biophysics (SCSB) combines thermodynamic, kinetic and structural data about biomolecules and their complexes to elucidate important biomedical processes. The structural and dynamical basis for molecular recognition, signal transduction, protein folding and allosteric regulation is studied by x-ray crystallographic, nuclear magnetic resonance, and cryo-electron microscopic techniques, solution thermodynamics and advanced computational tools.
In addition to its basic research goals, the SCSB provides education opportunities for post-docs and graduate students, and sponsors short courses and workshops for the faculty focusing on the use of NMR, cryo-EM, x-ray techniques, and molecular modeling tools. The annual symposium brings world renowned researchers together to exchange ideas in the warm sunshine of the Galveston/Houston area.